Выражение встречается в следующем контексте:

FDA is announcing the availability of a draft guidance for
reviewers entitled ``Integration of Study Results to Assess Concerns
About Human Reproductive and Developmental Toxicities.'' This draft
guidance describes a process for estimating human reproductive and
development risks as a result of drug exposure. The integration process
is intended to estimate the likelihood a drug will increase the risk of
adverse human reproductive or developmental effects. The process is
based on the evaluation of a complete set of reproductive and general
toxicology studies conducted in animals, pharmacokinetics, and the
absorption and distribution of metabolic elimination (ADME) studies
conducted in animals and humans. The evaluation also compares animal
and human drug-induced pharmacodynamic responses, drug metabolism and
disposition, drug-induced pharmacologic and toxic effects, and drug
exposures in animal studies versus those at the highest recommended
dose in humans.

Заранее спасибо
-Oles

четыре кита фармакокинетки: всасывание,распределение, метаболизм и выведение (или экскреция).

Аналогичного сокращения на русском не имеется.
Кроме того, похоже, в оригинале имеется ошибка. Мне как-то трудно представить себе "distribution **OF** (!) metabolic (!) elimination".