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link 4.12.2006 13:03 |
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Subject: dose-proportional formulations med. Доброго времени суток!Как по русски называются "dose-proportional formulations"? Это сочетание встретилось в тексте по фармакологии, точнее приготовлению лекарственных форм. Advantages of immediate release, dose-proportional formulations include improved ease of administration by allowing increases in dose without increasing the number of tablets that need to be administered, and increased flexibility in drug administration by allowing the target drug to be administered either as multiples of lower strength formulations or as one higher strength formulation. Another advantage of dose-proportional formulations of highly soluble and highly permeable drugs is that the bioavailability of multiple strengths, e.g., 10 mg versus 80 mg, are considered identical and in accordance with the guidelines, "Waiver of In Vivo Bioavailability and Bioequivalence Studies for Immediate-Release Solid Oral Dosage Forms Based on a Biopharmaceutics Classification System", U.S. Department of Health and Human Services, Food and Drug Administration. |
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link 4.12.2006 13:39 |
| Не назвать ли их "дозопропорциональными препаратами"? "Дозопропорциональный" встречается один раз в Яндексе. |
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