Выражение встречается в следующем контексте:Benhamou and colleagues found that tenofovir exhibited excellent anti-HBV activity in this group of patients. The median reduction in HBV DNA from baseline was 4.56 log10 copies/mL for HBeAg-positive patients and 2.53 log10 copies/mL for HBeAg-negative patients. At the end of the study, HBV DNA was
undetectable in 30% and 82% of the HBeAg-positive and HBeAg-negative individuals, respectively. A total of 4 HBeAg-positive patients experienced HBeAg loss, and 2 acquired serum anti-HBe antibodies. Tenofovir was found to be well-tolerated, with only 1 reported serious adverse event (renal tubulopathy).

Заранее спасибо