The retention of bretylium on the three bonded
phases Resolve C18, Symmetry C18 and XTerra MS
C18 with 50% acetonitrile (Fig. 3a) shows large
differences between the unendcapped Resolve C18
and the two newer phases. Resolve silica is a
lower purity silica. In addition, Resolve C18
is not endcapped. It therefore has a large silanol
deactivation of the silica due to endcapping and the
use of a high-purity silica reduces the retention of
bretylium to less than 1 in 50% acetonitrile and less
than 3.5 in 20% acetonitrile.

endcapping - допрививаться ??