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 dao2812

link 20.08.2016 12:05 
Subject: In some of these antibodies, the antibody is not any one of the antibodies or antibodies including CDR pharm.
Патент по антителам, в нем встечается такой фрагмент:

In some of these antibodies, the antibody is not any one of the antibodies or antibodies including CDRs (as defined by Kabat, Chothia or a composite thereof) entirely or substantially from the antibodies described in WO/2012/170071 and PCT/US2013/058773, particularly the antibodies designated clone 15 (defined by SEQ ID NOs:12-21) and clone 17 (defined by SEQ ID NOs:1-10) in WO/2012/170071 and the mouse anti-human MCAM monoclonal clones designated 1174.1.3, 1414.1.2, 1415.1.1, and 1749.1.3, and the rat anti-human MCAM monoclonal antibody clones designated 2120.4.19 and 2107.4.10 described in PCT/US2013/058773.

помогите, пожалуйста, перевести "In some of these antibodies, the antibody is not any one of the antibodies or antibodies including CDR"

предыдущий контекст:

The invention further provides non-antibody binding molecules. Non-antibody binding molecules include, for example, anticalins, which are based upon the lipocalin scaffold, a protein structure characterized by a rigid beta-barrel that supports four hypervariable loops which form the ligand binding site. Novel binding specificities are engineered by targeted random mutagenesis in the loop regions, in combination with functional display and guided selection

Заранее большое спасибо!

 

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