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Subject: germline region sequence biol. Помогите, пожалуйста, пеевести "germline region sequence" в котексте:A humanized antibody is a genetically engineered antibody in which the CDRs from a non-human “donor” antibody (i.e., 2120.4.19) are grafted into human “acceptor” antibody sequences. The acceptor antibody sequences can be, for example, a mature human antibody sequence, a composite of such sequences, a consensus sequence of human antibody sequences, or a germline region sequence. не совсем понтяно также, что есть "consensus sequence of human antibody sequences" и как перевести "are grafted into" Спасибо! |
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link 14.08.2016 5:01 |
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Googling for "germline antibody sequence" led me to this article But I don't understand fully the description of "germline antibodies" there. |
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link 14.08.2016 5:08 |
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Может быть, "последовательности из антител гаметического типа" (антител, не прошедших созревание аффинности (affinity maturation))? consensus sequence - консенсусная последовательность |
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link 14.08.2016 9:50 |
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стволовые клетки/пуповинная кровь maybe?... just guessing. |
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