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Subject: share receptor subunits biol. IL-2 and IL-15 share receptor subunits. However, the independent importance of IL-15 in maintenance of immune cell populations is undisputed; IL-15/IL-15R knockout mice exhibit low CD8+ T cells, low memory CD8+ T cells, and low NK cells, as well as other cell types (reviewed in Steel, J.C. et al. (2012) Interleukin-15 biology and its therapeutic implications in cancer, Trends in Pharmacological Sciences, 33(1):35-41).как правильно перевести "IL-2 and IL-15 share receptor subunits" смысл в том, что в рецепторах IL-2 и IL-15 содержатся субъединицы, общие для обоих интерлейкиов. Спасибо! |
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