Different tests were investigated including basophile degranulation by iron dextran, basophile histamine release, a type III anaphylactic reaction-specific IgG-antibodies and immune complex activation, specific IgG-antibodies against iron dextran. Only one patient had any test abnormalities. She had positive basophile histamine release and specific IgG-antibodies reversed and she declined at four months a
follow-up study. It seems that the mechanisms of iron dextran and anaphylactoid reactions are multiple and not yet clarified.

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