Toxicity information for PTFE decomposition products:
inhalation: PTFE decomposition products vary widely in toxicity in experimental animals.
Four hour LC50s (inhalation) for decomposition products range from 0.76 ppm (perfluoroisobutane) to 40,000 ppm (tetrafluoroethylene monomer). Workers exposed to PTFE fumes produced at 350-380 °C (temperatures associated with liberation of hexafluoroethane, perfluoroisobutylene, and octafluorocyclobutene) exhibited symptoms consistent with polymer fume fever at workplace air concentrations of 3.5 mg/m3 compounds containing fluorine.