| immunol. |
miniantibody (вариабельный сегмент антитела, полученный методами ограниченного протеолиза); minibody (An engineered antibody construct that consists of the variable-heavy- and variable-light-chain domains of a native antibody that is fused to the hinge region and to the CH3 domain of the immunogloblin molecule. Minibodies are small versions of whole antibodies, encoded in a single protein chain, that retain the antigen-binding region, the CH3 domain (to allow assembly into a bivalent molecule), and the antibody hinge (to accommodate dimerization by disulphide linkages). nature.com dzimmu) |
