Russian ⇄ English

крупные проблемы stresses
gen.	major issues (Secretary); serious problems (Ivan Pisarev); serious challenges (Ivan Pisarev); serious issues (Ivan Pisarev); serious difficulties (Ivan Pisarev); major challenges (Ivan Pisarev); major problems (Ivan Pisarev); major difficulties (Ivan Pisarev); significant challenges (Ivan Pisarev); significant problems (Ivan Pisarev); significant issues (Ivan Pisarev); significant difficulties (Ivan Pisarev); severe problems (Ivan Pisarev); severe challenges (Ivan Pisarev); severe issues (Ivan Pisarev); severe difficulties (Ivan Pisarev); grave problems (Ivan Pisarev); grave difficulties (Ivan Pisarev)
крупная проблема
adv.	major problem
formal	large issue (The opposition justice critic says this points to a larger issue in our justice system. -- это указывает на более крупную проблему ART Vancouver)
scient.	grand challenge (Alex_Odeychuk)

крупные проблемы: 4 phrases in 3 subjects

Energy industry	1
Information technology	1
Programming	2