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gen. have someone on edge (Александр_10); run something into the ground (бизнес: Personally I think Ms. Laura should get a job at another shop and let the owner run this one into the ground – by a Brides of California customer Tamerlane); push over the brink (Ремедиос_П); bother the hell out of (It херу ticking sound] wasn't very loud so you wouldn't even hear it in an "active" office but when you are in a quiet room by yourself it was fairly audible. Didn't bother me much but I can totally understand that it bothered the hell out of some people. ailon.org 4uzhoj)
Игорь Миг put someone on edge
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Idiomatic1