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впасть в уныниеstresses
gen. be at rock bottom; fall into despondence; become despondent (Leonid Dzhepko); get in the funk out (Ivan1992; that's uncommon one, could you at least give an example then, because that's a rare case? Luchemir); get discouraged (Sloneno4eg); be discouraged (Pokki)
Игорь Миг feel sick at heart
fig.of.sp. go into a brown study (Alex_Odeychuk)
Makarov. be cast down; be dejected; have one's heart in one's boots