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be en routestresses
gen. лететь (на самолете: Amanda Knox was en route to Seattle from Rome when David Thorne, the US ambassador to Italy, sent a cable to the State Department declaring that the case was officially over. 4uzhoj); направляться (куда-либо; об автомобиле, поезде, самолете и т. п.: Amanda Knox was en route to Seattle from Rome when David Thorne, the US ambassador to Italy, sent a cable to the State Department declaring that the case was officially over Taras); направляться (куда-либо; о поезде, самолете и т. п.: Remains left Torez on a train on the evening of 21 July, en route to Kharkiv to be flown to the Netherlands for identification. 4uzhoj); быть в пути (Taras)
fig. ожидать (there's one more startling surprise en route, right now. VLZ_58)