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 ochernen

link 7.01.2014 19:50 
Subject: Material-mediated Pyrogen Test med.
Acute Systemic Toxicity: Material-mediated Pyrogen Test

Речь идет о медицинских катетерах.
Что означает здесь Material-mediated Pyrogen Test? Просто проба на пирогенность материала (из которого катетер изготовлен)?

Заранее Благодарю.

 glomurka

link 7.01.2014 19:55 
Просто проба на пирогенность материала

http://www.pacificbiolabs.com/bio_methods.asp
The Material Mediated Pyrogen test evaluates the potential of a material to cause a pyrogenic response, or fever, when introduced into the blood.

http://www.toxikon.be/userfiles/files/biocompatibilityassessmentfdajapaneseguideline.pdf
Bacterial endotoxin contamination is most commonly associated with such an adverse effect; however, leachates of materials can cause similar febrile responses (material - mediated pyrogenicity). Material - mediated pyrogenicity assessment is typically included in biocompatibility assessment, while bacterial contamination and endotoxin - mediated pyrogenicity are issues related more to manufacturing processes than to biocompatibility of the device or material.

 Alex_Krotevich

link 7.01.2014 20:02 
+1 glomurka

 ochernen

link 7.01.2014 20:08 
Спасибо Уважаемые Коллеги :))

 

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