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Subject: oil vehicle pharm. Alternatively, delayed absorption of a parenterally administered drug form is accomplished by dissolving or suspending the drug in an oil vehicleСпасибо! |
| масло (в качестве растворителя) |
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vehicle = medium Врач подсказал. |
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я была бы осторожнее с medium, т.к. vehicle не всегда = medium. (с точки зрения технологии лекарственных форм и всяких клеточных экспериментов). лекарство сначала растворяют с помощью растворителя, а потом это все можно залить в medium, где это все сможет раствориться |
| На масляной основе, не? |
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Dao, а какая альтернатива перед этим указывалась? Скиньте несколько предложений до этого плз. |
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The injectable formulations can be sterilized, for example, by filtration through a bacterial-retaining filter, or by incorporating sterilizing agents in the form of sterile solid compositions which can be dissolved or dispersed in sterile water or other sterile injectable medium prior to use In order to prolong the effect of a drug, it is often desirable to slow the absorption of the drug from subcutaneous or intramuscular injection Я бы остановился на масле. Гидрофобный расворитель можно было бы. Но есть oil. Контекст насчет vehicle The pharmaceutical compositions of the present invention additionally comprise a pharmaceutically acceptable carrier, which, as used herein, includes any and all solvents, diluents, or other liquid vehicle, dispersion or suspension aids, surface active agents, isotonic agents, thickening or emulsifying agents, preservatives, solid binders, lubricants and the like, as suited to the particular dosage form desired Among the acceptable vehicles and solvents that may be employed are water, Ringer's solution, U.S.P. and isotonic sodium chloride solution. Alternatively, delayed absorption of a parenterally administered drug form is accomplished by dissolving or suspending the drug in an oil vehicle. The present inventors have also discovered that biodegradable liposomal delivery vehicles that have been surface-functionalized with a high density of negatively-charged groups and contain soluble antigen within their cores induce immunological tolerance in the R-EAE murine model of multiple sclerosis. |
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масло (скажем, растворить в масле перед приготовлением эмульсии и т.п.) vehicle - transports the active ingredient => например, двухфазное растворение, сначала активный ингредиент растворили в масле (vehicle), а потом часть этого раствора - в воде (solvent) |
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